According to the health survey conducted in the year 2015 in the UK, 62.9 % people were found obese or overweight. This high percentage of obese or overweight people is alarming as Obesity leads to many other diseases as hypertension, diabetes, joint pain etc. As per NHS survey in 2014-15, there were 9130 admissions reported for the treatment of obesity. As a result, there are various regimens such as bariatric surgery, caveats, oral medication, physical activity and diet plans came in action to treat overweight and obesity problem. If you are also one of those, whose BMI shows >27 or >30 kg/m2, Mysimba in the UK is a new drug which will help you out in fighting with obesity. Mysimba is approved in EU in 2015 as a weight loss drug.
According to European Medicines Agency report, published in Dec 2014, quality of Mysimba in the UK is satisfactory and acceptable.
Mysimba is a weight loss drug, manufactured by Orexigen therapeutics Ireland Ltd. It is a trending name in the UK in obesity treatment options these days. It is a combination of two active ingredients: Naltrexone hydrochloride and Bupropion hydrochloride. These ingredients are used independently to treat addiction and depression. When in combination as Mysimba, these molecules act on the brain and reduce cravings for food. This way, it changes your eating behavior and reduces calorie intake, thus ultimately reduces body weight. However, regular monitoring of the patient is needed for any changes in vital signs or psychological condition, while taking the drug. There are certain adverse effects as intolerable nausea, headache, constipation, dizziness, dryness of mouth, vomiting, and increase in resting heart rate. Serious neuropsychiatric effects can happen. If the patient has a history of seizures or neuropsychiatric disorder, then Mysimba treatment should be avoided.
Apart from weight loss benefit, there are other benefits of taking Mysimba such as reduced waist circumference, reduction in dangerous visceral fat, thus reduced risk of diabetes and cardiovascular diseases. Reduction in LDL (bad cholesterol) and triglycerides while improvement in glycemic index was observed in diabetic patients.
There are certain side effects of Mysimba which need to be observed, early and appropriate measures to be taken to minimize health risk. These side effects are insomnia, anxiety, restlessness, headache, mania, seizures, dizziness, lack of concentration, muscular pain, loss of appetite, constipation, nausea, hot flush. You should contact your doctor or call emergency medical services if any such symptom found. Vital signs should be checked on a regular basis when taking the drug.
Through NHS, Mysimba in the UK is evaluated on various criteria by London Medicines evaluation network(LMEN) review. According to LMEN review, Mysimba in the UK is hopefully a new weight loss drug and can be an alternative to existing obesity treatments such as weight loss surgery, weight management programs with targets, and pharmacological treatment with other obesity treatment drugs. NHS reviewed three clinical trial reports conducted in support of weight loss effects of naltrexone and bupropion together. Mysimba is critically evaluated by NHS in LMEN review on grounds of clinical application, safety, adverse events, risk assessment, convenience, potential advantage and disadvantage, drug cost, suitability for shared care with other disease and conditions. It is observed that Mysimba can be used to treat obesity along with lifestyle changes, physical exercise, and low-fat diet. In the UK Mysimba is available in prolonged release tablet form. The strength of the tablet is Naltrexone 7.2 mg + Bupropion 78 mg. Mysimba UK treatment starts with one tablet in the morning, then gradually the dosage increases to a maximum of two tablets in the morning and two tablets in the evening over four weeks. It is indicated to take Mysimba with food. Dosage varies in case of hepatic or renal impairment. It is recommended to stop taking my Simba if there is no change in weight loss even after 16 weeks of intake. However, Mysimba is a prescription drug and you need to take the drug as directed by your physician.
There are certain websites from where you will be able to order Mysimba in the UK. However, when you order the drug, physician consultation and an electronic prescription is provided before fulfilling your order. Affiliate physicians of these websites evaluate you and talk to you before they decide on your eligibility to take Mysimba treatment. When you order Mysimba in the UK online or offline, you need to verify the pharmacy to avoid taking fake Mysimba medication. If some websites accept your order without any prescription or physician consultation online, do not order from such pharmacies even if you can buy Mysimba at a cheaper price.
Since you are aware of the drug’s effects now, you can a “calculated” decision to go for this weight loss regimen and can ask the right questions to your physician regarding the treatment with this drug. Mysimba is not for everyone, every individual and his/her complaints differ from each other. Hence physician consultation (online or in person) is the best way to go for the drug.
Disclaimer: This article is for information purpose only. Please consult your physician before taking Mysimba drug.